Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 4/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.64 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.64 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674773 | 0.95 | HTR1A (0.60) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8675205 | 0.89 | PTGER1 (0.71) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8675521 | 0.86 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8675788 | 0.86 | PTGER1 (0.63) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8677422 | 0.85 | PTGER1 (0.65) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8674578 | 0.84 | PTGER4 (0.60) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL11066129 | 0.83 | HMGB1 (0.63) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL7050350 | 0.83 | PTGER1 (0.61) | PTGER1FOLH1MCL1HTTALDH1A1 | |
| SCHEMBL31557601 | 0.83 | ALDH1A1 (0.55) | PTGER1FOLH1MCL1HTTALDH1A1 | |
| SCHEMBL8677356 | 0.83 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |