Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.46 |
| ▸ | EP300 | Q09472 | 3/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496119 | 0.82 | ESR1 (0.43) | IDO1ESR1ESR2ARALDH1A1 | |
| SCHEMBL3433860 | 0.79 | IDO1 (0.52) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL10496125 | 0.78 | ESR1 (0.43) | IDO1ESR1ESR2ARALDH1A1 | |
| SCHEMBL16675604 | 0.77 | IDO1 (0.45) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL1581665 | 0.77 | ALDH1A1 (0.56) | ESR1ESR2ARALDH1A1TSHR | |
| SCHEMBL69219 | 0.77 | IDO1 (0.59) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL6399211 | 0.77 | IDO1 (0.59) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL11109601 | 0.76 | IDO1 (0.39) | IDO1ESR1ESR2ALDH1A1 | |
| SCHEMBL11549229 | 0.72 | HSD17B10 (0.44) | IDO1ALDH1A1TSHRTDP1 | |
| SCHEMBL11402389 | 0.71 | NQO2 (0.46) | ESR1ESR2ALDH1A1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483961-A | Polymeric cyclopentadiene derivatives, method for preparing and use thereof | ASHLAND OIL, INC. (US) | 1984-11-20 | — | — | US | disclosed |
| US-4482653-A | Cyclopentadiene derivatives, method for preparing, and use thereof | ASHLAND OIL, INC. (US) | 1984-11-13 | — | — | US | disclosed |
| US-4464521-A | EPOXIDIZED FULVENES AS BINDER FOR AGGREGATE; FOUNDRY BINDERS | ASHLAND OIL, INC. (US) | 1984-08-07 | — | — | US | disclosed |
| US-4412088-A | CURABLE BINDER COMPOSITIONS | ASHLAND OIL, INC. (US) | 1983-10-25 | — | — | US | disclosed |
| US-4390675-A | EPOXYFULVENE, ACID CATALYST | ASHLAND OIL, INC. (US) | 1983-06-28 | — | — | US | disclosed |