Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 3/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69219 | 0.86 | IDO1 (0.59) | IDO1ALDH1A1TSHRTDP1EP300 | |
| SCHEMBL7764200 | 0.86 | ALDH1A1 (0.60) | IDO1ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL5517816 | 0.85 | ALDH1A1 (0.48) | IDO1ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL3433860 | 0.81 | IDO1 (0.52) | IDO1ALDH1A1TSHRTDP1EP300 | |
| SCHEMBL20414568 | 0.78 | IDO1 (0.48) | IDO1ALDH1A1TSHRTDP1EP300 | |
| SCHEMBL6566550 | 0.77 | IDO1 (0.59) | IDO1TSHRTDP1EP300KAT2B | |
| SCHEMBL29362983 | 0.77 | IDO1 (1.00) | IDO1ALDH1A1TSHRTDP1EP300 | |
| SCHEMBL29638 | 0.77 | IDO1 (1.00) | IDO1ALDH1A1TSHRTDP1EP300 | |
| SCHEMBL32677325 | 0.77 | IDO1 (1.00) | IDO1ALDH1A1TSHRTDP1EP300 | |
| SCHEMBL23264379 | 0.77 | CA2 (0.56) | IDO1ALDH1A1TSHRTDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533766-A | Process for the production of dihydroxybenzenes | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-08-06 | — | — | US | claimed |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2023-10-12 | — | — | US | disclosed |
| US-20230313245-A1 | Engineered Enzymes and Method for the Synthesis of Diverse Tyrosine Analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-10-05 | — | — | US | disclosed |
| EP-4172160-A2 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-05-03 | — | — | EP | disclosed |
| US-20230132035-A1 | Toll-Like Receptor 8 (TLR8)-Specific Antagonists and Methods of Making and Uses Thereof | UNIV COLORADO REGENTS (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230132035-A1 | Toll-Like Receptor 8 (TLR8)-Specific Antagonists and Methods of Making and Uses Thereof | UNIV COLORADO REGENTS (US) | 2023-04-27 | — | — | US | disclosed |
| CN-115996928-A | 1' -cyanonucleoside analogs and uses thereof | 吉利德科学公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20230040586-A1 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-20220389021-A1 | INHIBITORS OF KRAS G12C | BEONE MEDICINES I GMBH (CH) | 2022-12-08 | — | — | US | disclosed |
| WO-2021262826-A2 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2021-12-30 | — | — | WO | disclosed |
| US-4533766-A | Process for the production of dihydroxybenzenes | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-08-06 | — | — | US | disclosed |
| US-4387252-A | HYDROXYLATION OF PHENOLS WITH PERACID COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1983-06-07 | — | — | US | disclosed |
| EP-0027593-B1 | PROCESS FOR THE PREPARATION OF POLYHYDRIC PHENOLS | BAYER AG (DE) | 1983-05-25 | — | — | EP | disclosed |
| US-4324925-A | Process for the preparation of polyhydric phenols | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| EP-0027593-A1 | Process for the preparation of polyhydric phenols | BAYER AG (DE) | 1981-04-29 | — | — | EP | disclosed |
| EP-0022533-A1 | Process for the preparation of polyvalent phenols | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4182918-A | Process for the preparation of polyhydric phenols | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |
| US-4174460-A | Process for the hydroxylation of phenols and phenol ethers in the nucleus | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-4077962-A | WATER INSOLUBLE, GREEN-YELLOW, SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-07 | — | — | US | disclosed |
| US-4045496-A | Process for the hydroxylation of phenols and phenol ethers in the nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132035-A1 | Toll-Like Receptor 8 (TLR8)-Specific Antagonists and Methods of Making and Uses Thereof | TLR8, TLR3, TLR9 | IDO1 894/4885ALDH1A1 4565/4885TSHR 500/4885 |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | IDO1 1773/4885ALDH1A1 3193/4885TSHR 2616/4885 |
| US-20230040586-A1 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | TYMP, PNP, DUT | IDO1 1618/4885ALDH1A1 1269/4885TSHR 4786/4885 |
| US-20220389021-A1 | INHIBITORS OF KRAS G12C | KRAS, NRAS, HRAS | IDO1 4566/4885ALDH1A1 3777/4885TSHR 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.