Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850480 | 0.80 | ALDH1A1 (0.62) | TSHRALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL2927687 | 0.80 | ALDH1A1 (0.62) | TSHRALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL3998923 | 0.79 | ALDH1A1 (0.49) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL4002343 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1KMT2ACYP2C19HIF1A | |
| SCHEMBL4002340 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1KMT2ACYP2C19HIF1A | |
| SCHEMBL4001984 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL4001990 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL7834770 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL16213089 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7650879 | 0.75 | ALDH1A1 (0.45) | TSHRALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074008-B1 | PROCESS FOR PRODUCING ALPHA-ARYLALKANOIC ACID ESTERS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4433160-A | Process for producing α-arylalkanoic acid ester | TAISHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
| EP-0074008-A2 | Process for producing alpha-arylalkanoic acid esters | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-03-16 | — | — | EP | disclosed |