Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927687 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TSHRCYP2C19HIF1AHTT | |
| SCHEMBL14850480 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TSHRCYP2C19HIF1AHTT | |
| SCHEMBL11066699 | 0.77 | TSHR (0.49) | ALDH1A1TSHRCYP2C19HIF1AHTT | |
| SCHEMBL4002343 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP2C19HIF1AHTT | |
| SCHEMBL4002340 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP2C19HIF1AHTT | |
| SCHEMBL4001984 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP2C19HIF1AHTT | |
| SCHEMBL4001990 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP2C19HIF1AHTT | |
| SCHEMBL6758034 | 0.74 | CYP2C19 (0.50) | ALDH1A1TSHRCYP2C19HIF1AKMT2A | |
| SCHEMBL1492728 | 0.74 | CYP2C19 (0.50) | ALDH1A1TSHRCYP2C19HIF1AKMT2A | |
| SCHEMBL29336758 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C19HIF1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077957-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058510-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-18 | — | — | WO | disclosed |