Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NADK | O95544 | 2/20 | 0.79 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.78 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | GAPDH | P04406 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | HBB | P68871 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.62 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12030991 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL20419274 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL6671819 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL14435669 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL13587343 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL440925 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL440926 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL29707221 | 0.99 | NADK (0.78) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL28823544 | 0.99 | NADK (0.78) | NADKHSPA8HSPA5RXFP1GAPDH | |
| Phosphoric Acid SCHEMBL8628967 | 0.94 | NADK (0.72) | NADKHSPA8HSPA5RXFP1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153609-B2 | Purine nucleotide derivatives | LAURAS AS (NO) | 2012-04-10 | — | — | US | disclosed |
| US-20080293665-A1 | Purine Nucleotide Derivatives | LAURAS AS (NO) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293665-A1 | Purine Nucleotide Derivatives | CGAS, PDE8A, PDE7A | NADK 301/4885HSPA8 2075/4885HSPA5 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.