Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NADK | O95544 | 2/20 | 0.79 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.78 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | GAPDH | P04406 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | HBB | P68871 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.62 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12030991 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL20419274 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL6671819 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL13587343 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL440925 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL440926 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL1106674 | 1.00 | NADK (0.79) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL29707221 | 0.99 | NADK (0.78) | NADKHSPA8HSPA5RXFP1GAPDH | |
| SCHEMBL28823544 | 0.99 | NADK (0.78) | NADKHSPA8HSPA5RXFP1GAPDH | |
| Phosphoric Acid SCHEMBL8628967 | 0.94 | NADK (0.72) | NADKHSPA8HSPA5RXFP1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| WO-2007091056-A2 | BICYCLIC COMPOUNDS AND THEIR USE | THE UNIVERSITY OF YORK (GB) | 2007-08-16 | — | — | WO | disclosed |