Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401319 | 0.98 | MGAM (0.44) | MGAMGAASIMGAM2CYP2D6 | |
| SCHEMBL27456435 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KMT2ALMNASMN1; SMN2HSD17B10 | |
| SCHEMBL13465760 | 0.79 | MGAM (0.43) | MGAMGAASIMGAM2CYP2D6 | |
| SCHEMBL27515213 | 0.79 | NAAA (0.44) | ALDH1A1KMT2ANPSR1ATM | |
| SCHEMBL10916991 | 0.77 | CYP4F2 (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL12818018 | 0.77 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28014498 | 0.76 | CYP4F2 (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28082070 | 0.75 | CYP1A2 (0.48) | GAACYP2D6ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL25664507 | 0.74 | GAA (0.57) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL472103 | 0.74 | ALDH1A1 (0.47) | GAAALDH1A1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450270-A | Dioximino cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1984-05-22 | — | — | US | disclosed |
| US-4402955-A | ZWITTERIONS; GRAMNEGATIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1983-09-06 | — | — | US | disclosed |