SCHEMBL11066840

SCHEMBL11066840

COCC(=O)N(CCl)c1c(C)cccc1C

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
LMNA P02545 3/20 0.39
GAA P10253 1/20 0.37
OPRM1 P35372 2/20 0.36
SIGMAR1 Q99720 2/20 0.36
RORC P51449 1/20 0.36
THRB P10828 2/20 0.36
GRM5 P41594 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NLRP3 Q96P20 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11067755 0.86 ALDH1A1 (0.55) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL11794677 0.84 ALDH1A1 (0.44) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL9614333 0.83 ALDH1A1 (0.57) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL28269636 0.83 TP53 (0.42) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL11147283 0.83 TP53 (0.39) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL16284697 0.81 ALDH1A1 (0.49) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL14320112 0.81 NLRP3 (0.39) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL11149744 0.80 TP53 (0.37) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL11122498 0.80 ALDH1A1 (0.44) TP53ALDH1A1CYP3A4TDP1MEN1
SCHEMBL11263200 0.79 ALDH1A1 (0.51) TP53ALDH1A1CYP3A4TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4478848-A Combating fungi with substituted anilinomethylene-oximes BAYER AKTIENGESELLSCHAFT (DE) 1984-10-23 US disclosed
EP-0072970-A1 Substituted anilinomethylene oximes, method for their preparation and their use as herbicides BAYER AG (DE) 1983-03-02 EP disclosed