Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629391 | 0.72 | EPHX2 (0.54) | BRD4CREBBPEPHX2SMN1; SMN2CASP3 | |
| SCHEMBL11071961 | 0.69 | DDB1 (0.50) | BRD4CREBBPEPHX2BRPF1GAA | |
| SCHEMBL11071691 | 0.69 | GAA (0.44) | BRD4CREBBPEPHX2BRPF1GAA | |
| SCHEMBL23123532 | 0.68 | ALDH1A1 (0.45) | BRD4CREBBPBRPF1GAASMN1; SMN2 | |
| SCHEMBL29789812 | 0.68 | ALDH1A1 (0.45) | BRD4CREBBPBRPF1GAASMN1; SMN2 | |
| SCHEMBL2629324 | 0.68 | BRD4 (0.65) | BRD4CREBBPEPHX2BRPF1GAA | |
| SCHEMBL22004371 | 0.67 | BRPF1 (0.40) | BRD4CREBBPEPHX2BRPF1GAA | |
| SCHEMBL13347976 | 0.67 | ALDH1A1 (0.47) | BRD4CREBBPBRPF1GAASMN1; SMN2 | |
| SCHEMBL4048986 | 0.66 | GAA (0.44) | BRD4CREBBPEPHX2BRPF1GAA | |
| SCHEMBL4703417 | 0.66 | GAA (0.44) | BRD4CREBBPEPHX2BRPF1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477464-A | Hetero-benzazepine derivatives and their pharmaceutical use | CIBA-GEIGY CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |