Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 17/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073298 | 0.86 | ABCB1 (0.61) | ABCB1SCN1ASCN5ASCN9A | |
| SCHEMBL11070828 | 0.85 | OPRL1 (0.47) | OPRL1POLB | |
| SCHEMBL10570390 | 0.85 | MAPT (0.56) | ABCB1SCN1ASCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL10570172 | 0.84 | MAPT (0.55) | ABCB1SCN1ASCN5ASCN9A | |
| SCHEMBL11061136 | 0.83 | KCNH2 (0.56) | ABCB1SCN1ASCN5ASCN9A | |
| SCHEMBL11065039 | 0.83 | DRD4 (0.60) | ABCB1 | |
| SCHEMBL11729211 | 0.83 | HTR6 (0.48) | ABCB1POLB | |
| Oxalic Acid SCHEMBL11071627 | 0.81 | ABCB1 (0.58) | ABCB1 | |
| SCHEMBL11067274 | 0.80 | ABCB1 (0.48) | ABCB1 | |
| SCHEMBL11066891 | 0.76 | ABCB1 (0.61) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |