Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065079 | 0.83 | BRD4 (0.35) | BRD4GAAPOLBHPGDALDH1A1 | |
| SCHEMBL11065362 | 0.83 | BRD4 (0.55) | BRD4GAAPOLBHPGDALDH1A1 | |
| SCHEMBL11067691 | 0.80 | POLB (0.49) | GAAPOLBKMT2AL3MBTL1MAPT | |
| SCHEMBL11073784 | 0.79 | POLB (0.56) | GAAPOLBKMT2AALDH1A1MAPT | |
| SCHEMBL11076964 | 0.78 | POLB (0.41) | BRD4GAAPOLBKMT2AALDH1A1 | |
| SCHEMBL11267150 | 0.75 | ALDH1A1 (0.38) | BRD4GAAPOLBKMT2AALDH1A1 | |
| SCHEMBL11072919 | 0.73 | BRD4 (0.49) | BRD4GAAPOLBHPGDKMT2A | |
| SCHEMBL3823508 | 0.72 | BRD4 (0.58) | BRD4GAAHPGDKMT2AALDH1A1 | |
| SCHEMBL11260515 | 0.71 | BRD4 (0.49) | BRD4GAAPOLBALDH1A1L3MBTL1 | |
| SCHEMBL3826958 | 0.71 | BRD4 (0.59) | BRD4GAAHPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020293-B1 | STABILISING COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-05-23 | — | — | EP | claimed |
| US-4309546-A | Piperidino pyrrolidinones | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | claimed |
| EP-0020293-A1 | Stabilising compounds, process for their preparation and compositions containing them | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | claimed |
| US-4309546-A | Piperidino pyrrolidinones | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |