Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826958 | 0.90 | BRD4 (0.59) | BRD4SMN1; SMN2KMT2AP2RX7HPGD | |
| SCHEMBL28956225 | 0.83 | BRD4 (0.67) | BRD4SMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL30282498 | 0.83 | BRD4 (0.67) | BRD4SMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL12667142 | 0.83 | BRD4 (0.67) | BRD4SMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL3826291 | 0.80 | POLB (0.58) | BRD4KMT2AP2RX7HPGDALDH1A1 | |
| SCHEMBL1362127 | 0.77 | BRD4 (0.63) | BRD4SMN1; SMN2KMT2AP2RX7HPGD | |
| SCHEMBL15042223 | 0.77 | BRD4 (0.63) | BRD4SMN1; SMN2KMT2AP2RX7HPGD | |
| SCHEMBL3829040 | 0.77 | ALDH1A1 (0.42) | BRD4KMT2AHPGDALDH1A1LMNA | |
| SCHEMBL3822795 | 0.76 | BRD4 (0.61) | BRD4SMN1; SMN2KMT2AP2RX7HPGD | |
| SCHEMBL12368059 | 0.75 | BRD4 (0.59) | BRD4SMN1; SMN2KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |