Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TLR4 | O00206 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375448 | 0.92 | MEN1 (0.57) | HTR6F10MEN1KMT2ATDP1 | |
| SCHEMBL1963579 | 0.89 | HTR6 (0.56) | HTR6F10MEN1KMT2ATDP1 | |
| SCHEMBL16792372 | 0.89 | ALDH1A1 (0.57) | HTR6F10MEN1KMT2ATDP1 | |
| SCHEMBL10337453 | 0.87 | HTR6 (0.52) | HTR6F10MEN1KMT2ATDP1 | |
| SCHEMBL10717379 | 0.86 | ALDH1A1 (0.55) | HTR6MEN1KMT2ATDP1TTR | |
| SCHEMBL11315551 | 0.85 | MEN1 (0.58) | HTR6F10MEN1KMT2ATDP1 | |
| SCHEMBL1298266 | 0.85 | MERTK (0.52) | HTR6F10MEN1KMT2ATDP1 | |
| SCHEMBL10424095 | 0.84 | MEN1 (0.55) | HTR6F10MEN1KMT2ATDP1 | |
| SCHEMBL646471 | 0.84 | MEN1 (0.54) | F10MEN1KMT2ATDP1TTR | |
| SCHEMBL30061165 | 0.84 | MEN1 (0.54) | F10MEN1KMT2ATDP1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027555-B1 | PROCESS FOR THE PREPARATION OF DIPHENYL ETHERS | CELAMERCK GmbH & Co. KG (DE) | 1984-01-04 | — | — | EP | disclosed |
| US-4364875-A | AMINATION, ISOMER-FREE END-PRODUCTS | CELAMERCK GMBH & CO. KG (DE) | 1982-12-21 | — | — | US | disclosed |
| EP-0027555-A1 | Process for the preparation of diphenyl ethers | CELAMERCK GmbH & Co. KG (DE) | 1981-04-29 | — | — | EP | disclosed |