SCHEMBL11067923

SCHEMBL11067923

Cc1cc(CON)sc1C

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AGXT P21549 4/20 0.44
RIPK1 Q13546 1/20 0.36
IDO1 P14902 7/20 0.35
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
DAO P14920 1/20 0.33
KMT2A Q03164 1/20 0.33
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1169964 0.75
SCHEMBL1364286 0.71 TAAR1 (0.38) RIPK1KDM4EMEN1ALDH1A1MAPT
SCHEMBL11246897 0.70
SCHEMBL14117321 0.68 RIPK1 (0.41) RIPK1KDM4EMEN1ALDH1A1MAPT
SCHEMBL3460385 0.68 RIPK1 (0.35) RIPK1
SCHEMBL19435063 0.67 PRMT6 (0.48) RIPK1KDM4EMEN1ALDH1A1MAPT
SCHEMBL14093052 0.67 RIPK1 (0.44) RIPK1KDM4EMEN1ALDH1A1MAPT
SCHEMBL16418570 0.64 HRH3 (0.37) RIPK1ALDH1A1
SCHEMBL13141021 0.64
SCHEMBL3444431 0.64 MAPT (0.50) RIPK1KDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4432786-A Thienylmethoxyiminoalkyl cyclohexanedione herbicides CHEVRON RESEARCH COMPANY (US) 1984-02-21 US disclosed