Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | F7 | P08709 | 4/20 | 0.49 |
| ▸ | F3 | P13726 | 4/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | FABP3 | P05413 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067937 | 1.00 | ALDH1A1 (0.49) | ALDH1A1PPARGKDM4EF7F3 | |
| SCHEMBL11797581 | 0.99 | PPARG (0.47) | ALDH1A1PPARGKDM4EF7F3 | |
| SCHEMBL9336094 | 0.86 | PTPN7 (0.48) | ALDH1A1KDM4ECYP3A4TDP1FAAH | |
| SCHEMBL9529939 | 0.86 | PTPN7 (0.48) | ALDH1A1KDM4ECYP3A4TDP1FAAH | |
| SCHEMBL14873844 | 0.86 | PTPN7 (0.48) | ALDH1A1KDM4ECYP3A4TDP1FAAH | |
| SCHEMBL1101207 | 0.86 | PTPN7 (0.48) | ALDH1A1KDM4ECYP3A4TDP1FAAH | |
| SCHEMBL1089589 | 0.84 | PTPN7 (0.46) | ALDH1A1KDM4ECYP3A4TDP1HPGD | |
| SCHEMBL11063903 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PPARGKDM4EF7F3 | |
| SCHEMBL11063890 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PPARGKDM4EF7F3 | |
| SCHEMBL11794235 | 0.80 | PPARG (0.57) | ALDH1A1PPARGKDM4EF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456619-A | Amides of 2-alkynoic acids and use for inhibiting accumulation of cholesterol ester in arterial walls | SANDOZ, INC. (US) | 1984-06-26 | — | — | US | disclosed |