Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.48 |
| ▸ | HMGCR | P04035 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14873844 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRRECQLTDP1ALDH1A1 | |
| SCHEMBL1101207 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRRECQLTDP1ALDH1A1 | |
| SCHEMBL9336094 | 1.00 | PTPN7 (0.48) | PTPN7HMGCRRECQLTDP1ALDH1A1 | |
| SCHEMBL1089589 | 0.98 | PTPN7 (0.46) | PTPN7HMGCRRECQLTDP1ALDH1A1 | |
| SCHEMBL1088906 | 0.92 | HMGCR (0.40) | PTPN7HMGCRRECQLTDP1ALDH1A1 | |
| SCHEMBL29248381 | 0.87 | PTPN7 (0.47) | PTPN7HMGCRRECQLTDP1ALDH1A1 | |
| SCHEMBL9336139 | 0.87 | CYP4F2 (0.43) | PTPN7HMGCRALDH1A1MEN1KMT2A | |
| SCHEMBL11067939 | 0.86 | ALDH1A1 (0.49) | PTPN7RECQLTDP1ALDH1A1MAPT | |
| SCHEMBL11067937 | 0.86 | ALDH1A1 (0.49) | PTPN7RECQLTDP1ALDH1A1MAPT | |
| SCHEMBL4229900 | 0.85 | NAAA (0.47) | PTPN7HMGCRRECQLTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |