Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.64 |
| ▸ | DRD2 | P14416 | 7/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066723 | 0.93 | DRD2 (0.65) | KCNH2DRD2DRD3DRD4MAOA | |
| SCHEMBL11070256 | 0.90 | DRD2 (0.63) | KCNH2DRD2DRD3DRD4HTR1A | |
| SCHEMBL11070211 | 0.90 | DRD2 (0.65) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11062760 | 0.89 | DRD2 (0.57) | KCNH2DRD2DRD3DRD4HTR1A | |
| SCHEMBL11063552 | 0.89 | DRD2 (0.62) | KCNH2DRD2DRD3DRD4HTR1A | |
| SCHEMBL11068660 | 0.84 | DRD2 (0.61) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11065637 | 0.84 | DRD2 (0.63) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11064417 | 0.84 | DRD2 (0.76) | KCNH2DRD2DRD3DRD4HTR1A | |
| SCHEMBL11069040 | 0.84 | DRD2 (0.61) | KCNH2DRD2DRD3DRD4HTR1A | |
| SCHEMBL11071886 | 0.84 | DRD2 (0.63) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |