Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.61 |
| ▸ | DRD3 | P35462 | 5/20 | 0.59 |
| ▸ | DRD4 | P21917 | 4/20 | 0.59 |
| ▸ | HTR1A | P08908 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | HTR2C | P28335 | 4/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.59 |
| ▸ | HTR7 | P34969 | 3/20 | 0.59 |
| ▸ | MAOA | P21397 | 10/20 | 0.58 |
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
| ▸ | DRD5 | P21918 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
| ▸ | HTR3B | O95264 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068613 | 0.92 | DRD2 (0.69) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11066469 | 0.91 | DRD2 (0.61) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11063552 | 0.88 | DRD2 (0.62) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11064417 | 0.86 | DRD2 (0.76) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11070211 | 0.86 | DRD2 (0.65) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11068571 | 0.84 | KCNH2 (0.64) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11062760 | 0.84 | DRD2 (0.57) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11068038 | 0.84 | DRD2 (0.68) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL23097785 | 0.83 | DRD2 (0.82) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11060146 | 0.83 | DRD2 (0.60) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |