Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283981 | 0.82 | TDP1 (0.51) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL10975446 | 0.80 | MEN1 (0.48) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL10976216 | 0.78 | KMT2A (0.49) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL11126859 | 0.78 | ALDH1A1 (0.52) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL11047126 | 0.77 | TDP1 (0.56) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL10883530 | 0.76 | TDP1 (0.71) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL10482222 | 0.75 | TLR8 (0.60) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL10975930 | 0.75 | MEN1 (0.57) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL10983781 | 0.75 | KMT2A (0.47) | TDP1MEN1KMT2ATTRALB | |
| SCHEMBL8360647 | 0.75 | MAPT (0.41) | TDP1MEN1KMT2ATTRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027555-B1 | PROCESS FOR THE PREPARATION OF DIPHENYL ETHERS | CELAMERCK GmbH & Co. KG (DE) | 1984-01-04 | — | — | EP | disclosed |