Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TLR4 | O00206 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983781 | 0.97 | KMT2A (0.47) | KMT2AMEN1TTRALBTHRB | |
| SCHEMBL10975446 | 0.91 | MEN1 (0.48) | KMT2AMEN1TTRALBTHRB | |
| SCHEMBL22555908 | 0.83 | ALDH1A1 (0.54) | KMT2AMEN1TTRALBTHRB | |
| SCHEMBL3689752 | 0.78 | LTA4H (0.55) | KMT2AMEN1TDP1MAPTTSHR | |
| SCHEMBL11068601 | 0.78 | TDP1 (0.49) | KMT2AMEN1TTRALBTHRB | |
| SCHEMBL11048022 | 0.77 | TDP1 (0.51) | KMT2AMEN1TTRALBTHRB | |
| SCHEMBL11069630 | 0.76 | TDP1 (0.57) | KMT2AMEN1TTRALBTHRB | |
| SCHEMBL11601180 | 0.76 | MEN1 (0.47) | KMT2AMEN1TTRALBTHRB | |
| SCHEMBL11126859 | 0.75 | ALDH1A1 (0.52) | KMT2AMEN1TTRALBTHRB | |
| SCHEMBL22555942 | 0.75 | MAPT (0.48) | KMT2AMEN1TTRALBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4532350-A | Process for the selective preparation of meta-chloroanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-07-30 | — | — | US | disclosed |
| EP-0045709-B1 | PROCESS FOR THE PREPARATION OF META-CHLORINATED ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1984-10-03 | — | — | EP | disclosed |
| EP-0045710-B1 | PROCESS FOR THE SELECTIVE PREPARATION OF META-CHLORINATED ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1984-07-04 | — | — | EP | disclosed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | disclosed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | disclosed |
| EP-0015220-B1 | PROCESS FOR THE PREPARATION OF META-CHLORO ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1982-05-12 | — | — | EP | disclosed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | disclosed |
| EP-0045709-A1 | Process for the preparation of meta-chlorinated anilines | RHONE-POULENC AGROCHIMIE (FR) | 1982-02-10 | — | — | EP | disclosed |
| EP-0045710-A1 | Process for the selective preparation of meta-chlorinated anilines | RHONE-POULENC AGROCHIMIE (FR) | 1982-02-10 | — | — | EP | disclosed |
| EP-0015219-B1 | PROCESS FOR THE PREPARATION OF META-CHLORO ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1981-10-28 | — | — | EP | disclosed |
| EP-0015220-A1 | Process for the preparation of meta-chloro anilines | RHONE-POULENC AGROCHIMIE (FR) | 1980-09-03 | — | — | EP | disclosed |
| EP-0015219-A1 | Process for the preparation of meta-chloro anilines | RHONE-POULENC AGROCHIMIE (FR) | 1980-09-03 | — | — | EP | disclosed |