Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206947 | 0.96 | IDO1 (0.46) | KDM4EIDO1AKR1C3MAPTHTT | |
| SCHEMBL11068617 | 0.78 | HTT (0.48) | KDM4EMAPTHTTHPGDALDH1A1 | |
| SCHEMBL31120281 | 0.77 | TACR1 (0.42) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31120346 | 0.77 | KMT2A (0.47) | IDO1HTTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL30963181 | 0.77 | IDO1 (0.58) | IDO1AKR1C3MAPTALDH1A1RAB9A | |
| SCHEMBL7445879 | 0.77 | TACR1 (0.47) | ALDH1A1CYP1A2KMT2A | |
| SCHEMBL7795558 | 0.76 | ALDH1A1 (0.43) | KDM4EMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6424076 | 0.76 | IDO1 (0.53) | IDO1AKR1C3MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27461289 | 0.76 | KDM4E (0.51) | KDM4EIDO1MAPTHTTHPGD | |
| SCHEMBL2367956 | 0.76 | MEN1 (0.56) | KDM4EMAPTHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447605-A | Di(tri-lower alkylstannyl)pyrimidine derivative and a process for producing the same | RIKAGAKU KENKYUSHO (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4324895-A | REACTION BETWEEN BIS(TRI-LOWER ALKYLSTANNYL)-5-HALOGENOURACIL AND 2-SUBSTITUTED TETRAHYDROFURAN | RIKAGAKU KENKYUSHO (JP) | 1982-04-13 | — | — | US | disclosed |