Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095108 | 0.95 | HTT (0.44) | HTTKDM4ECES2CES1CYP1A2 | |
| SCHEMBL16021495 | 0.95 | HTT (0.44) | HTTKDM4ECES2CES1CYP1A2 | |
| SCHEMBL31357139 | 0.92 | CES2 (0.46) | HTTCES2CES1POLBLMNA | |
| SCHEMBL27006326 | 0.84 | KMT2A (0.54) | HTTCYP1A2CYP2D6HPGDPOLB | |
| SCHEMBL1025068 | 0.79 | SLC6A2 (0.52) | POLBLMNAALDH1A1 | |
| SCHEMBL11068614 | 0.78 | KDM4E (0.49) | HTTKDM4ECYP1A2CYP2D6HPGD | |
| SCHEMBL3500438 | 0.77 | TNK2 (0.44) | KDM4EHPGDPOLBLMNAKMT2A | |
| SCHEMBL2367956 | 0.76 | MEN1 (0.56) | HTTKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL1157242 | 0.76 | PDE4B (0.50) | HTTLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL15214979 | 0.75 | ALDH1A1 (0.41) | KDM4EHPGDPOLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447605-A | Di(tri-lower alkylstannyl)pyrimidine derivative and a process for producing the same | RIKAGAKU KENKYUSHO (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4324895-A | REACTION BETWEEN BIS(TRI-LOWER ALKYLSTANNYL)-5-HALOGENOURACIL AND 2-SUBSTITUTED TETRAHYDROFURAN | RIKAGAKU KENKYUSHO (JP) | 1982-04-13 | — | — | US | disclosed |
| US-4297129-A | HERBICIDES; WILD OATS; NONPHYTOTOXIC | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-27 | — | — | US | disclosed |