Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302495 | 0.85 | HRH3 (0.63) | HRH3HTR2CHTR2BMAOAMAOB | |
| SCHEMBL10274499 | 0.83 | SLC6A4 (0.55) | HRH3HTR2CHTR2BSMN1; SMN2FPR2 | |
| SCHEMBL5469425 | 0.81 | SLC6A2 (0.56) | HRH3MAOAMAOBSMN1; SMN2FPR2 | |
| SCHEMBL12192961 | 0.80 | WNT1 (0.46) | HRH3MAOAMAOBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5467944 | 0.79 | SLC6A2 (0.54) | HRH3MAOAMAOBSMN1; SMN2FPR2 | |
| SCHEMBL17433283 | 0.78 | HRH3 (0.50) | HRH3HTR2CHTR2BMAOAMAOB | |
| SCHEMBL12192917 | 0.78 | IKBKB (0.60) | HRH3MAOAMAOBSMN1; SMN2 | |
| SCHEMBL10077964 | 0.78 | HRH3 (0.54) | HRH3HTR2CHTR2BMAOAMAOB | |
| SCHEMBL11073591 | 0.78 | IKBKB (0.60) | HRH3HTR2CHTR2BSLC6A4 | |
| SCHEMBL31729440 | 0.77 | MAOA (0.48) | HRH3MAOAMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |