Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359843 | 0.91 | CYP3A4 (0.47) | IDO1ALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL11709637 | 0.88 | IDO1 (0.41) | IDO1ALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL11684698 | 0.83 | ALDH1A1 (0.43) | IDO1ALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL10359841 | 0.81 | TSHR (0.68) | IDO1ALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL11450814 | 0.81 | TP53 (0.50) | ALDH1A1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11441977 | 0.79 | TP53 (0.49) | ALDH1A1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24699931 | 0.78 | CYP1A2 (0.47) | IDO1ALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL8955369 | 0.78 | TP53 (0.47) | ALDH1A1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7070645 | 0.77 | IDO1 (0.55) | IDO1ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL4334537 | 0.76 | S1PR4 (0.61) | TP53TSHRTDP1S1PR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468510-A | FILMS, FIBERS, MOLDING PLASTICS, LOW GAS PERMEABILITY | EASTMAN KODAK COMPANY (US) | 1984-08-28 | — | — | US | disclosed |