Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441977 | 0.98 | TP53 (0.49) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL11450814 | 0.92 | TP53 (0.50) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL10359843 | 0.86 | CYP3A4 (0.47) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL27904038 | 0.84 | TDP1 (0.67) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL8955424 | 0.84 | TDP1 (0.67) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL28740947 | 0.81 | GPR84 (0.43) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL8778565 | 0.81 | MRGPRX4 (0.43) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL7228434 | 0.80 | GPR84 (0.47) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL2097932 | 0.78 | MRGPRX4 (0.45) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL8955786 | 0.78 | ALDH1A1 (0.69) | TP53CYP1A2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |