Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077024 | 0.90 | LMNA (0.42) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11080350 | 0.88 | ABCB11 (0.44) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11073420 | 0.87 | ABCB11 (0.51) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11077144 | 0.86 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11073550 | 0.86 | ABCB11 (0.53) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11071660 | 0.86 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11070066 | 0.86 | SPHK1 (0.44) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11076754 | 0.85 | ABCB11 (0.51) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11073753 | 0.85 | ABCB11 (0.51) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11080379 | 0.84 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |