Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25130936 | 0.81 | POLB (0.44) | POLBTDP1KDM4EALDH1A1MAPT | |
| SCHEMBL1291135 | 0.81 | POLB (0.59) | POLBTDP1KDM4EGPR35ALDH1A1 | |
| SCHEMBL13590586 | 0.78 | ALDH1A1 (0.44) | TDP1KDM4EGPR35ALDH1A1MAPK1 | |
| SCHEMBL3407348 | 0.78 | ALDH1A1 (0.48) | POLBTDP1KDM4EGPR35ALDH1A1 | |
| SCHEMBL29199004 | 0.76 | MCL1 (0.55) | POLBTDP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2128678 | 0.76 | ALDH1A1 (0.56) | POLBTDP1KDM4EGPR35ALDH1A1 | |
| SCHEMBL31199000 | 0.76 | ALDH1A1 (0.56) | POLBTDP1KDM4EGPR35ALDH1A1 | |
| SCHEMBL26287686 | 0.76 | S1PR1 (0.39) | KDM4EGPR35ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17141437 | 0.75 | POLB (0.43) | POLBTDP1KDM4EALDH1A1MAPT | |
| SCHEMBL6742273 | 0.75 | TDP1 (0.66) | POLBTDP1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474602-A | Substituted pyridyl compounds, herbicidal compositions and method of use | THE DOW CHEMICAL COMPANY (US) | 1984-10-02 | — | — | US | disclosed |