Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19330148 | 0.84 | TDP1 (0.61) | POLBTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL19330176 | 0.82 | TDP1 (0.59) | POLBTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL30701048 | 0.82 | TDP1 (0.59) | POLBTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL11069140 | 0.81 | POLB (0.45) | POLBTDP1KDM4EALDH1A1PRKAG1 | |
| SCHEMBL10426645 | 0.81 | POLB (0.45) | POLBTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL16986595 | 0.77 | POLB (0.41) | POLBTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL198490 | 0.74 | TDP1 (1.00) | POLBTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL1905326 | 0.74 | TDP1 (0.53) | POLBTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL30539297 | 0.74 | TDP1 (0.53) | POLBTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL29859234 | 0.74 | TDP1 (1.00) | POLBTDP1LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103140486-B | Co-crystals and salts of CCR 3-inhibitors | 贝林格尔.英格海姆国际有限公司 | 2016-08-03 | — | — | CN | disclosed |
| US-9233950-B2 | Co-crystals and salts of CCR3-inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-20150105371-A1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-16 | — | — | US | disclosed |
| EP-2625174-B1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2015-01-21 | — | — | EP | disclosed |
| US-8742115-B2 | Co-crystals and salts of CCR3-inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-03 | — | — | US | disclosed |
| US-20140135307-A1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| EP-2625174-A1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2013-08-14 | — | — | EP | disclosed |
| US-20120264729-A1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-18 | — | — | US | disclosed |
| WO-2012045803-A1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264729-A1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | CCR3, CCR1, CCR4 | POLB 4432/4885TDP1 3572/4885LMNA 3494/4885 |
| US-20140135307-A1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | CCR3, CCR1, CCR4 | POLB 4432/4885TDP1 3572/4885LMNA 3494/4885 |
| US-20150105371-A1 | CO-CRYSTALS AND SALTS OF CCR3-INHIBITORS | CCR3, CCR1, CCR4 | POLB 4432/4885TDP1 3572/4885LMNA 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.