Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066576 | 0.89 | OPRL1 (0.36) | SKP2IRAK4OPRL1MLNRBACE1 | |
| SCHEMBL11066524 | 0.83 | MLNR (0.37) | SKP2IRAK4OPRL1MLNRBACE1 | |
| SCHEMBL11078319 | 0.82 | OPRL1 (0.41) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11073165 | 0.81 | OPRL1 (0.34) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11071470 | 0.75 | SKP2 (0.40) | SKP2OPRL1BACE1OPRM1 | |
| SCHEMBL11069281 | 0.73 | OPRL1 (0.46) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11071467 | 0.72 | SKP2 (0.38) | SKP2OPRL1BACE1OPRM1 | |
| SCHEMBL11069606 | 0.72 | OPRL1 (0.40) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11074417 | 0.71 | SKP2 (0.43) | SKP2MLNRBACE1 | |
| SCHEMBL11074165 | 0.71 | OPRL1 (0.44) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |