Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.34 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.34 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074078 | 0.87 | GRIN2B (0.40) | SKP2DRD2DRD3OPRM1OPRL1 | |
| SCHEMBL11070718 | 0.81 | SKP2 (0.35) | SKP2SPHK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11076092 | 0.81 | HTR1D (0.38) | SKP2SPHK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11071467 | 0.80 | SKP2 (0.38) | SKP2SPHK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11074417 | 0.79 | SKP2 (0.43) | SKP2CYP3A4CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL11066524 | 0.78 | MLNR (0.37) | SKP2SLC6A4SPHK1CYP3A4CYP2D6 | |
| SCHEMBL11066576 | 0.78 | OPRL1 (0.36) | SKP2CYP3A4CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL11077902 | 0.76 | SLC6A4 (0.39) | SLC6A4SLC6A3DRD2DRD4DRD3 | |
| SCHEMBL11069269 | 0.75 | SKP2 (0.34) | SKP2BACE1OPRM1OPRL1 | |
| SCHEMBL11071936 | 0.74 | SLC6A4 (0.39) | SLC6A4SLC6A3DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |