Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 8/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071372 | 0.87 | OPRL1 (0.39) | OPRL1OPRM1OPRK1HTR2AHTR2C | |
| SCHEMBL11075482 | 0.81 | OPRL1 (0.40) | OPRL1OPRM1OPRK1HTR2AHTR2C | |
| SCHEMBL11069269 | 0.81 | SKP2 (0.34) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11078319 | 0.78 | OPRL1 (0.41) | OPRL1OPRM1OPRK1HTR2AHTR2C | |
| SCHEMBL11069281 | 0.75 | OPRL1 (0.46) | OPRL1OPRM1OPRK1CCR2 | |
| SCHEMBL11069606 | 0.74 | OPRL1 (0.40) | OPRL1OPRM1OPRK1SLC6A4 | |
| SCHEMBL11074165 | 0.73 | OPRL1 (0.44) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11079377 | 0.73 | OPRL1 (0.45) | OPRL1OPRM1 | |
| SCHEMBL11071936 | 0.72 | SLC6A4 (0.39) | OPRL1OPRM1HTR2AHTR2CSLC6A4 | |
| SCHEMBL11072181 | 0.72 | OPRL1 (0.43) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |