Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10538554 | 0.84 | PNP (0.44) | GAAPKMTSHRPNPSMN1; SMN2 | |
| SCHEMBL11063731 | 0.80 | PNP (0.43) | GAAPKMTSHRPNPSMN1; SMN2 | |
| SCHEMBL10537739 | 0.80 | PNP (0.46) | GAAPKMTSHRPNPSMN1; SMN2 | |
| SCHEMBL10541524 | 0.78 | PDE4A (0.43) | GAAPKMTSHRPNPSMN1; SMN2 | |
| SCHEMBL10542779 | 0.76 | PNP (0.40) | GAAPKMTSHRPNPSMN1; SMN2 | |
| SCHEMBL10537609 | 0.74 | HCAR1 (0.41) | CYP11B2 | |
| SCHEMBL10537628 | 0.74 | HCAR1 (0.43) | HPGDALDH1A1 | |
| SCHEMBL10538796 | 0.73 | HCAR1 (0.42) | HPGDALDH1A1MAPK14 | |
| SCHEMBL11067389 | 0.72 | PNP (0.46) | GAAPKMTSHRPNPSMN1; SMN2 | |
| SCHEMBL10538430 | 0.72 | HPGD (0.38) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460585-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1984-07-17 | — | — | US | disclosed |