Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069383 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL10621126 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHPGDALDH1A1AKT1 | |
| SCHEMBL10621121 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHPGDALDH1A1AKT1 | |
| SCHEMBL7425739 | 0.79 | TDP1 (0.65) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL7425727 | 0.79 | TDP1 (0.65) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL9435294 | 0.77 | MAPT (0.48) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL1168553 | 0.76 | SLC1A2 (0.66) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL9462009 | 0.76 | SLC1A2 (0.66) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL1168551 | 0.76 | SLC1A2 (0.66) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL14397456 | 0.75 | LMNA (0.54) | SMN1; SMN2LMNAGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435329-A | ANTIHYPERTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-06 | — | — | US | disclosed |