Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069532 | 0.74 | SMN1; SMN2 (0.51) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL11696189 | 0.74 | POLB (0.60) | ABL1MAPK1PIK3CAMAPK8MAPK9 | |
| SCHEMBL11069813 | 0.73 | ADORA2B (0.44) | ABL1ADORA2BMAPK1ADORA2AADORA1 | |
| SCHEMBL11072262 | 0.72 | PIK3CA (0.54) | ABL1PIK3CA | |
| SCHEMBL2552184 | 0.72 | — | — | |
| SCHEMBL11066718 | 0.72 | ADORA2B (0.44) | ABL1ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL11065275 | 0.71 | ADORA2B (0.45) | ABL1ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL13904343 | 0.71 | ABL1 (0.47) | ABL1MAPK1PIK3CAMAPK8MAPK9 | |
| SCHEMBL11065170 | 0.70 | ADORA2B (0.47) | ABL1ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL2550762 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448780-A | N-(Lower-alkyl)-N'-[5-(pyridinyl)-2-pyridinyl]ureas and cardiotonic use thereof | STERLING DRUG INC. (US) | 1984-05-15 | — | — | US | disclosed |