Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320295 | 1.00 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TDP1POLBKDM4E | |
| SCHEMBL11507269 | 0.92 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TDP1POLBKDM4E | |
| SCHEMBL11140575 | 0.90 | SMN1; SMN2 (0.48) | ALDH1A1TDP1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL22773398 | 0.88 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TDP1POLBKDM4E | |
| SCHEMBL11136289 | 0.88 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TDP1POLBKDM4E | |
| SCHEMBL11222403 | 0.88 | RAB9A (0.47) | ALDH1A1TDP1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL11779730 | 0.87 | RAB9A (0.56) | ALDH1A1HSD17B10TDP1POLBRAB9A | |
| SCHEMBL11066543 | 0.83 | RAB9A (0.50) | ALDH1A1TDP1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL11655623 | 0.83 | TSHR (0.50) | ALDH1A1TDP1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7734041 | 0.82 | TDP1 (0.58) | ALDH1A1HSD17B10TDP1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483795-A | Substituted phenyl disazo dyes containing a 2-amino-substituted thiazole radical | BASF AKTIENGESELLSCHAFT (DE) | 1984-11-20 | — | — | US | disclosed |
| US-4372885-A | Bisazo dyes containing a 2-amino-substituted thiazole radical | BASF AKTIENGESELLSCHAFT (DE) | 1983-02-08 | — | — | US | disclosed |