Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 14/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 14/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312325 | 0.90 | PDE3B (0.60) | PDE3BPDE3APDE2AP2RY12PDE4A | |
| SCHEMBL11320635 | 0.87 | PDE3B (0.64) | PDE3BPDE3APDE2AP2RY12PDE4A | |
| SCHEMBL11312191 | 0.82 | PDE3B (0.53) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11316229 | 0.79 | PDE3B (0.51) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11066038 | 0.79 | PDE3B (0.47) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11317207 | 0.78 | PDE3B (0.52) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11313442 | 0.78 | PDE3B (0.43) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11281273 | 0.76 | ADRB2 (0.49) | ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL11062523 | 0.76 | PDE3B (0.49) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11066100 | 0.76 | ADRB1 (0.43) | PDE3BPDE3AADRB2ADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |