Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067420 | 0.94 | BCL2 (0.35) | ALDH1A1MAPK1TDP1TSHRL3MBTL1 | |
| SCHEMBL11074512 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1TDP1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL3827846 | 0.78 | L3MBTL1 (0.40) | ALDH1A1MAPK1TDP1TSHRL3MBTL1 | |
| SCHEMBL31316615 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1TDP1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3826956 | 0.78 | L3MBTL1 (0.39) | ALDH1A1MAPK1TDP1TSHRL3MBTL1 | |
| SCHEMBL11816273 | 0.77 | SMN1; SMN2 (0.42) | ALDH1A1MAPK1TDP1TSHRL3MBTL1 | |
| SCHEMBL9463438 | 0.75 | BCL2 (0.35) | ALDH1A1MAPK1TDP1TSHRL3MBTL1 | |
| SCHEMBL17700331 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1TSHRL3MBTL1 | |
| SCHEMBL9666338 | 0.73 | BCL2 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL6898820 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461771-A | PROPHYLAXIS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1984-07-24 | — | — | US | disclosed |