Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | S100A4 | P26447 | 2/20 | 0.55 |
| ▸ | BCL2 | P10415 | 6/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046162 | 0.86 | MCL1 (0.50) | HSP90AA1S100A4BCL2MCL1TSHR | |
| SCHEMBL11072946 | 0.83 | BCL2 (0.67) | S100A4BCL2MCL1HSD17B10ALDH1A1 | |
| SCHEMBL27428387 | 0.82 | BCL2 (0.72) | S100A4BCL2MCL1TSHRHSD17B10 | |
| SCHEMBL4229683 | 0.82 | S100A4 (0.80) | HSP90AA1S100A4BCL2MCL1TSHR | |
| SCHEMBL353693 | 0.82 | S100A4 (0.80) | HSP90AA1S100A4BCL2MCL1TSHR | |
| SCHEMBL4319897 | 0.82 | S100A4 (0.71) | HSP90AA1S100A4ESR1MAOAUGT1A1 | |
| SCHEMBL29581505 | 0.82 | S100A4 (0.71) | HSP90AA1S100A4ESR1MAOAUGT1A1 | |
| SCHEMBL3279172 | 0.78 | S100A4 (0.67) | HSP90AA1S100A4BCL2MCL1ESR1 | |
| SCHEMBL30345128 | 0.77 | S100A4 (0.90) | HSP90AA1S100A4ESR1MAOAUGT1A1 | |
| SCHEMBL1133148 | 0.77 | S100A4 (0.90) | HSP90AA1S100A4ESR1MAOAUGT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447420-A | Fluorenone esters of phosphoric and phosphonic acids as insecticides | VELSICOL CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |