Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66550 | 0.84 | ENPP2 (0.60) | NPC1MAPTRAB9ASMN1; SMN2ENPP2 | |
| SCHEMBL11628676 | 0.82 | HTT (0.56) | MAPTSMN1; SMN2HPGDENPP2PHLPP2 | |
| SCHEMBL11804192 | 0.81 | ENPP2 (0.55) | NPC1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL11290527 | 0.79 | ENPP2 (0.55) | NPC1MAPTRAB9ASMN1; SMN2AMY1A | |
| SCHEMBL9477426 | 0.78 | ENPP2 (0.51) | NPC1MAPTRAB9AENPP2PHLPP2 | |
| SCHEMBL13578938 | 0.78 | SENP2 (0.56) | MAPTRAB9AHPGDTHRBPKM | |
| SCHEMBL1436156 | 0.78 | SENP2 (0.60) | MAPTHPGDTHRBPHLPP2CYP2C19 | |
| SCHEMBL2622737 | 0.78 | SENP2 (0.56) | MAPTRAB9AHPGDTHRBPKM | |
| SCHEMBL31099405 | 0.78 | SENP2 (0.60) | MAPTHPGDTHRBPHLPP2CYP2C19 | |
| SCHEMBL110924 | 0.78 | SENP2 (0.60) | MAPTHPGDTHRBPHLPP2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036838-B1 | AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-09-26 | — | — | EP | disclosed |
| US-4447357-A | Fibre-reactive azo dyestuffs containing a halotriazinyl radical and a non-reactive triazinyl radical | CIBA-GEIGY CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0036838-A2 | Azo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| US-3960831-A | WET FASTNESS, COLORFASTNESS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |