Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070716 | 0.85 | OPRM1 (0.34) | OPRM1SLC6A4SLC6A2TSHRHTR3A | |
| SCHEMBL11079745 | 0.84 | OPRM1 (0.34) | OPRM1SLC6A4HTR3A | |
| SCHEMBL11075481 | 0.84 | OPRM1 (0.38) | OPRM1SLC6A4SLC6A2TSHRHTR3A | |
| SCHEMBL11069869 | 0.83 | OPRM1 (0.36) | OPRM1SLC6A4SLC6A2TSHRHTR3A | |
| SCHEMBL11075246 | 0.81 | OPRM1 (0.35) | OPRM1SLC6A4SLC6A2TSHRHTR3A | |
| SCHEMBL11076803 | 0.80 | OPRM1 (0.35) | OPRM1SLC6A4SLC6A2TSHRHTR3A | |
| SCHEMBL11071918 | 0.80 | OPRM1 (0.36) | OPRM1SLC6A4SLC6A2TSHRHTR3A | |
| SCHEMBL11070717 | 0.79 | OPRM1 (0.38) | OPRM1SLC6A4SLC6A2TSHRHTR3A | |
| SCHEMBL11079742 | 0.78 | OPRM1 (0.36) | OPRM1SLC6A4SLC6A2HTR3A | |
| SCHEMBL11071938 | 0.78 | OPRK1 (0.40) | OPRM1SLC6A4SLC6A2OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |