Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075471 | 0.94 | OPRM1 (0.44) | OPRL1OPRM1DRD2HTR1ADRD1 | |
| SCHEMBL11079138 | 0.93 | DRD3 (0.43) | OPRL1OPRM1DRD2HTR1ADRD1 | |
| SCHEMBL11076919 | 0.91 | OPRL1 (0.43) | OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL11081934 | 0.90 | OPRL1 (0.51) | OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL11073740 | 0.89 | OPRL1 (0.41) | OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL11073542 | 0.89 | OPRM1 (0.42) | OPRL1OPRK1OPRM1 | |
| SCHEMBL11076003 | 0.88 | OPRD1 (0.47) | OPRL1OPRM1OPRD1 | |
| SCHEMBL11076240 | 0.87 | OPRM1 (0.44) | OPRL1OPRK1OPRM1OPRD1HTR7 | |
| SCHEMBL11076093 | 0.84 | OPRL1 (0.50) | OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL11073866 | 0.83 | OPRM1 (0.41) | OPRL1OPRK1OPRM1OPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |