Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | F7 | P08709 | 4/20 | 0.41 |
| ▸ | F3 | P13726 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | FABP3 | P05413 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068322 | 1.00 | FAAH (0.49) | FAAHMGLLALDH1A1PPARGKDM4E | |
| SCHEMBL11068321 | 1.00 | FAAH (0.49) | FAAHMGLLALDH1A1PPARGKDM4E | |
| SCHEMBL11064315 | 0.96 | FAAH (0.43) | FAAHMGLLPPARGF7F3 | |
| SCHEMBL11063371 | 0.96 | FAAH (0.43) | FAAHMGLLPPARGF7F3 | |
| SCHEMBL11064727 | 0.96 | FAAH (0.43) | FAAHMGLLPPARGF7F3 | |
| SCHEMBL11070761 | 0.96 | FAAH (0.43) | FAAHMGLLPPARGF7F3 | |
| SCHEMBL11064725 | 0.96 | FAAH (0.43) | FAAHMGLLPPARGF7F3 | |
| SCHEMBL11063515 | 0.94 | FAAH (0.43) | FAAHMGLLPPARGF7F3 | |
| SCHEMBL11070754 | 0.89 | PTPN7 (0.39) | ALDH1A1KDM4EHPGDTDP1PTPN7 | |
| SCHEMBL11066474 | 0.89 | PTPN7 (0.39) | ALDH1A1KDM4EHPGDTDP1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456619-A | Amides of 2-alkynoic acids and use for inhibiting accumulation of cholesterol ester in arterial walls | SANDOZ, INC. (US) | 1984-06-26 | — | — | US | disclosed |