SCHEMBL11069978

SCHEMBL11069978

CCOC(=NC(=O)NCc1ccc(OC(F)(F)C(Cl)Cl)cc1)c1c(F)cccc1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 7/20 0.40
PPARG P37231 3/20 0.40
PPARA Q07869 2/20 0.40
OPRM1 P35372 1/20 0.36
NR1H4 Q96RI1 1/20 0.35
FAAH O00519 1/20 0.35
HTR2C P28335 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
ALDH1A1 P00352 1/20 0.34
ATM Q13315 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
KLKB1 P03952 1/20 0.34
PPID Q08752 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11074228 0.91 MEN1 (0.38) EPHX2PPARGPPARAOPRM1NR1H4
SCHEMBL11079072 0.90 EPHX2 (0.40) EPHX2PPARGPPARANR1H4HTR2C
SCHEMBL11073508 0.89 CNR1 (0.36) EPHX2PPARGPPARAOPRM1NR1H4
SCHEMBL11068997 0.87 POLB (0.38) EPHX2KMT2AMEN1ALDH1A1NPC1
SCHEMBL11068999 0.87 POLB (0.38) EPHX2KMT2AMEN1ALDH1A1NPC1
SCHEMBL11078044 0.84 EPHX2 (0.40) EPHX2PPARGPPARAALDH1A1NPC1
SCHEMBL11079539 0.83 EPHX2 (0.39) EPHX2PPARGPPARAKMT2ANPC1
SCHEMBL11075301 0.81 LMNA (0.39) EPHX2OPRM1NR1H4HTR2CKMT2A
SCHEMBL11069971 0.80 TLR7 (0.39) PPARAKMT2AMEN1ALDH1A1NPC1
SCHEMBL11069973 0.80 TLR7 (0.39) PPARAKMT2AMEN1ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431667-A Imino ethers useful for controlling insect and arachnoid pests THE UPJOHN COMPANY (US) 1984-02-14 US disclosed