SCHEMBL11073508

SCHEMBL11073508

CC(C)OC(=NC(=O)NCc1ccc(OC(F)(F)C(Cl)Cl)cc1)c1c(F)cccc1F

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
OPRM1 P35372 1/20 0.36
EPHX2 P34913 4/20 0.35
NR1H4 Q96RI1 2/20 0.35
HTR2C P28335 1/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
PPARA Q07869 2/20 0.33
PPARG P37231 1/20 0.33
S1PR3 Q99500 1/20 0.33
TLR8 Q9NR97 1/20 0.33
FAAH O00519 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11074228 0.91 MEN1 (0.38) CNR1CNR2OPRM1EPHX2NR1H4
SCHEMBL11073529 0.90 CARM1 (0.38) CNR1CNR2OPRM1EPHX2NR1H4
SCHEMBL11069978 0.89 EPHX2 (0.40) OPRM1EPHX2NR1H4HTR2CMEN1
SCHEMBL11079005 0.86 TLR8 (0.41) EPHX2NPC1RAB9ATRPV1TLR8
SCHEMBL11079027 0.86 TLR8 (0.41) EPHX2NPC1RAB9ATRPV1TLR8
SCHEMBL11072603 0.84 TDP1 (0.37) CNR1CNR2EPHX2NR1H4ALDH1A1
SCHEMBL11077930 0.83 PPARD (0.36) EPHX2NR1H4KMT2ANPC1RAB9A
SCHEMBL11075301 0.81 LMNA (0.39) OPRM1EPHX2NR1H4HTR2CMEN1
SCHEMBL11119140 0.80 LMNA (0.47) EPHX2ALDH1A1NPC1RAB9ATLR8
SCHEMBL11119143 0.80 LMNA (0.47) EPHX2ALDH1A1NPC1RAB9ATLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431667-A Imino ethers useful for controlling insect and arachnoid pests THE UPJOHN COMPANY (US) 1984-02-14 US disclosed