Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070000 | 1.00 | SPHK1 (0.43) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11069649 | 0.97 | SPHK1 (0.40) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11069662 | 0.97 | SPHK1 (0.40) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11075813 | 0.95 | SPHK1 (0.43) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11075810 | 0.95 | SPHK1 (0.43) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11066531 | 0.91 | RAB9A (0.41) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11066526 | 0.91 | RAB9A (0.41) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11069741 | 0.91 | SPHK1 (0.44) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11070006 | 0.91 | GAA (0.39) | SPHK1MAPTRAB9AGAAHSD17B10 | |
| SCHEMBL11070008 | 0.91 | GAA (0.39) | SPHK1MAPTRAB9AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462923-A | Disubstituted pyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1984-07-31 | — | — | US | disclosed |