Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HPD | P32754 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069457 | 0.94 | OPRM1 (0.50) | ALOX5BCHEOPRM1OPRL1KDM1A | |
| Ethylene SCHEMBL11550591 | 0.92 | OPRM1 (0.48) | ALOX5BCHEOPRM1OPRL1KDM1A | |
| SCHEMBL11071011 | 0.91 | ALOX5 (0.52) | ALOX5BCHEOPRM1OPRL1KDM1A | |
| SCHEMBL11120660 | 0.90 | ALOX5 (0.49) | ALOX5KDM1ALTB4RLTB4R2MAOB | |
| Ethylene SCHEMBL11099478 | 0.89 | ALOX5 (0.50) | ALOX5BCHEOPRM1OPRL1KDM1A | |
| SCHEMBL11072760 | 0.89 | ALOX5 (0.52) | ALOX5BCHEOPRM1OPRL1KDM1A | |
| SCHEMBL11074085 | 0.89 | ALOX5 (0.56) | ALOX5BCHEOPRM1OPRL1KDM1A | |
| SCHEMBL11077877 | 0.85 | ALOX5 (0.48) | ALOX5OPRM1OPRL1KDM1AMAOB | |
| SCHEMBL11067153 | 0.85 | ALOX5 (0.45) | ALOX5OPRM1OPRL1KDM1ALTB4R | |
| SCHEMBL11075817 | 0.82 | OPRM1 (0.45) | ALOX5BCHEOPRM1OPRL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |