Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437911 | 0.86 | POLB (0.51) | HSD17B10L3MBTL1MAPTSQSTM1KEAP1 | |
| SCHEMBL15935612 | 0.84 | HSD17B10 (0.70) | HSD17B10MAPTAKR1C3AKR1C2KDM4E | |
| SCHEMBL16372583 | 0.83 | MEN1 (0.50) | HSD17B10L3MBTL1MAPTSQSTM1KEAP1 | |
| SCHEMBL16267829 | 0.83 | KDM4E (0.52) | HSD17B10L3MBTL1MAPTSQSTM1KEAP1 | |
| SCHEMBL16930126 | 0.83 | THRB (0.51) | HSD17B10L3MBTL1MAPTSQSTM1KEAP1 | |
| SCHEMBL20232451 | 0.83 | PPARG (0.53) | L3MBTL1MAPTSQSTM1KEAP1NFE2L2 | |
| SCHEMBL7083444 | 0.83 | NQO1 (0.56) | HSD17B10L3MBTL1MAPTAKR1C3AKR1C2 | |
| SCHEMBL2168667 | 0.77 | AKR1C3 (0.48) | HSD17B10L3MBTL1MAPTSQSTM1KEAP1 | |
| SCHEMBL686360 | 0.77 | KDM4E (0.54) | HSD17B10L3MBTL1MAPTAKR1C3AKR1C2 | |
| SCHEMBL10607711 | 0.77 | NQO1 (0.48) | HSD17B10L3MBTL1MAPTAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426536-A | Synthesis of phenylacetic acid esters | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0098058-A1 | Synthesis of phenylacetic acid esters | ELI LILLY AND COMPANY (US) | 1984-01-11 | — | — | EP | disclosed |