Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169394 | 0.88 | AKR1C3 (0.44) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL11479123 | 0.86 | ALDH1A1 (0.44) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL453836 | 0.86 | AKR1C2 (0.59) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL11468637 | 0.79 | MPL (0.54) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL7801636 | 0.78 | MPL (0.47) | ALDH1A1HPGDSMN1; SMN2TSHRMAPT | |
| SCHEMBL7808139 | 0.78 | CYSLTR1 (0.56) | — | |
| SCHEMBL2169163 | 0.77 | TSHR (0.43) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL11070050 | 0.77 | HSD17B10 (0.50) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL21437911 | 0.77 | POLB (0.51) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL2169159 | 0.76 | AKR1C3 (0.71) | AKR1C3AKR1C2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709819-B2 | Preparation and its use of derivatization reagent for detecting L-carnitine or D-carnitine | GU SHUHUA (CN) | 2014-04-29 | — | — | US | disclosed |
| EP-2348315-B1 | PREPARATION AND ITS USE OF DERIVATISATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | CHANGZHOU MULTIPLE DIMENSION INST OF INDUSTRY TECHNOLOGY CO LTD (CN) | 2013-12-18 | — | — | EP | disclosed |
| US-20110281293-A1 | PREPARATION AND ITS USE OF DERIVATIZATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | GU SHUHUA (CN) | 2011-11-17 | — | — | US | disclosed |
| EP-2348315-A1 | PREPARATION AND ITS USE OF DERIVATISATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | Changzhou Multiple Dimension Institute Of Industry Technology Co., Ltd. (CN) | 2011-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281293-A1 | PREPARATION AND ITS USE OF DERIVATIZATION REAGENT FOR DETECTING L-CARNITINE OR D-CARNITINE | CRAT, CPT1B, SLC25A20 | AKR1C3 1211/4885AKR1C2 876/4885KDM4E 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.