SCHEMBL11070082

SCHEMBL11070082

Oc1cc(Cc2ccccc2)c(O)c2ccccc12

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.64
BCL2L1 Q07817 1/20 0.64
ALOX5 P09917 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19051165 0.89 KEAP1 (0.56) BCL2BCL2L1ALOX5
SCHEMBL8772360 0.85 HMGB1 (0.56) BCL2BCL2L1
SCHEMBL9748732 0.82 CYP2C9 (0.57) BCL2BCL2L1
SCHEMBL9748771 0.81 PTPN1 (0.51) BCL2BCL2L1
SCHEMBL9747950 0.81 BCL2 (0.50) BCL2BCL2L1
SCHEMBL18604567 0.79 BCL2 (1.00) BCL2BCL2L1ALOX5
SCHEMBL2514742 0.79 BCL2 (0.82) BCL2BCL2L1ALOX5
SCHEMBL5663542 0.79 PTPN1 (0.47) BCL2BCL2L1
SCHEMBL9748865 0.79 PTPN1 (0.64) BCL2
SCHEMBL9861413 0.78 BCL2 (0.46) BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4460681-A COLOR FORMING LAYERS, AND SOLVENT SOLUBLE BARRIE LAYERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-17 US disclosed